About Plenful

Plenful is on a mission to move pharmacy forward through intelligent automation. We build AI-powered software that eliminates administrative burden, strengthens compliance, and unlocks revenue across critical pharmacy workflows, solving one of the biggest challenges in healthcare today: delayed patient care.

Built by a passionate team of former healthcare operators and world-class AI technologists, Plenful combines deep domain expertise with enterprise-grade technology to automate complex workflows across intake authorization, 340B program optimization, and pharmacy revenue reconciliation. Our AI platform is trusted by 95+ leading healthcare organizations to power smarter, faster, and more resilient pharmacy operations.

Backed by leading investors including Notable Capital, Bessemer Venture Partners, and TQ Ventures, Plenful is building the institutional memory for healthcare and powering the most complex, highest ROI healthcare workflows. We’re actively hiring as we continue to scale.

Learn more about our values and origin story at https://www.plenful.com/company.

About the role
We’re hiring Senior Product Managers to join our founding PM team. As we enter our next phase of growth, we’re focused on productizing solutions that solve complex customer problems at scale. We’re looking for PMs who bring structure, ownership, strong customer intuition, and a builder mindset.

If you’ve thrived in fast-moving, resource-constrained environments and want the ownership and leadership proximity that comes with being an early product hire at a high-growth company, this role is for you.

What you’ll do

• Lead product development from discovery to launch — partnering closely with engineering, design, customer success, and go-to-market teams to ship impactful, high-quality solutions.
• Own your product area end-to-end: customer discovery, roadmap definition, prioritization, execution, and iteration.
• Translate complex operational workflows into elegant, scalable product solutions that create measurable outcomes for customers.
• Define and track success metrics — using data, user feedback, and business objectives to validate hypotheses and guide decisions.
• Build an internal feedback flywheel with customer success and support to continuously surface and act on customer intelligence.
• Work directly with executive leadership — you’ll have the access, the visibility, and the accountability that comes with it.
• Navigate healthcare compliance and privacy considerations (HIPAA, payor requirements, auditability) as a core part of product design, not an afterthought.

What we’re looking for

• Must-Have
• 5+ years of Product Management experience, with a track record of success in high-growth, scrappy environments.
• Experience in B2B software or enterprise SaaS.
• Zero-to-One Mindset: Proven ability to build products from the ground up where no playbook exists.
• Strong product instincts: can distill complex, messy workflows into elegant solutions and make defensible prioritization decisions under ambiguity.
• Excellent communication — you can write a crisp PRD, present to a CTO, and run a customer discovery session with equal confidence.
• Analytical and data-driven — you use metrics to make decisions, not to justify them after the fact.
• Genuine curiosity about the problem space — you want to work on hard, ignored problems because you care about the impact, not just the resume line.

Strong-to-Have

• Experience shipping AI-powered or LLM-powered features to production.
• Platform PM or API product experience.
• 0-to-1 product launch experience.
• Experience in regulated or compliance-driven product environments (fintech, healthcare, legal, government).

Why Join Now

• Define the product function — you’re joining a founding PM team, not fitting into an established org.
• Work directly with world-class leadership — CPO, CTO, and CEO proximity from day one.
• Meaningful equity at a company with real traction.
• Named to TechCrunch AI Disruptors 60.
• Greenfield technical opportunity — our context graph architecture is a genuinely novel system that gets smarter as frontier models improve.

Plenful perks

• Comprehensive Benefits Package: Enjoy unlimited PTO, fully covered health insurance (medical, dental, and vision),  meal stipend, health & wellness stipend, 401(k) matching, and stock options
• Mission-Driven, World-Class Team: Join an exceptional group of professionals aligned around a meaningful mission and committed to making an impact
• Opportunities for Growth: Strengthen your partnership expertise through collaboration with experienced, high-performing leaders across the organization
• Flexible Hybrid Work Environment: We are a remote-first company with meaningful office presence in San Francisco and New York. R&D roles follow a hybrid model, with two days per week in our San Francisco office.