About Alto Neuroscience, Inc.

At Alto Neuroscience, you will play a pivotal role in advancing precision psychiatry and improving how mental health disorders are treated. Join us in building the next generation of personalized neuroscience-based therapeutics.

Primary Role

The Head of Biometrics provides executive oversight and leadership for Alto’s clinical data strategy across Phase 2 and Phase 3 development programs. 

This role bridges the gap between complex data and strategic business decisions, transforming clinical outputs into intuitive visual narratives that drive execution. Serving as a grounded subject matter expert and people leader you will orchestrate a lean, high-performing mix of internal strategy and external /consultants to support Alto’s precision psychiatry portfolio.

What you'll do

• Strategic Enterprise Leadership: Lead the holistic biometrics strategy, spanning data management, statistical strategy, programming, and data visualization, to support corporate objectives and clinical milestones across Phase 2/3 CNS trials.
• Data Visualization & Storytelling: Design, interpret, and present clear, intuitive data visualizations and dashboards that translate complex quantitative outputs into actionable, decision-ready insights for executive leadership, board members, and cross-functional teams.
• Consultant & Vendor Orchestration: Direct and manage external vendors and specialized statistical consultants; hold partner teams accountable for high-quality, timely deliverables including SAPs, database locks, TLFs, and regulatory submissions.
• Practical Subject Matter Expertise: Serve as the internal voice of authority on biometrics strategy, knowing how to evaluate trial design, endpoints, and data integrity without needing to perform hand-rolled statistical derivations.
• Cross-Functional Partnership: Collaborate seamlessly with Clinical Operations, Medical, Translational Medicine, Regulatory, and Engineering to integrate data workflows, support health authority interactions, and streamline precision medicine/digital endpoint strategies.
• Scalable Operations & Governance: Build scalable data processes, standards (CDISC, SDTM/ADaM), and vendor management frameworks to support Alto’s growth from mid-stage clinical trials into commercial readiness.

Location

Mountain View, CA onsite is preferred; may consider remote candidates depending on experience

Salary Range

$320,000 to 350,000

*depending on qualifications and experience level

Qualifications

Required Skills:

• Education: Master’s degree in Biostatistics, Data Science, Statistics, Quantitative Health Sciences, or a related field (Ph.D. not required).
• Enterprise Leadership & Vendor Management: Proven track record of leading biometrics/data functions in biotech or pharma, with heavy experience managing contractors, and specialized statistical consultants.
• Data Visualization & Communication: Demonstrated mastery in creating clear, compelling data visualizations and communicating complex analytical concepts to non-statistical stakeholders and executive management.
• Balanced Technical Judgment: Strong foundational knowledge of Phase 2/3 clinical trial design, regulatory expectations, and CDISC standards, with the discernment to know when standard methods suffice versus when to call in deep technical specialists.
• Cross-Functional Influence: Exceptional collaboration and project management skills with a pragmatic, business-minded approach to problem-solving in a fast-paced environment.

Preferred Skills:

• Prior experience building, scaling, or leading a biometrics function in a growing biotech company.
• Prior experience supporting clinical development in CNS, psychiatry, or mood disorders.
• Experience with biomarker-stratified trials, precision medicine, digital endpoints, or data-driven clinical development approaches.
• Experience supporting NDA, BLA, MAA, or other major regulatory submissions.

Physical Demands & Work Environment:

• Required to sit for prolonged periods of time.
• While performing the duties of this job, the noise level in the work environment is usually quiet.

Alto Neuroscience is an equal-opportunity employer that does not discriminate on the basis of sex, age, race, color, religion, marital status, sexual orientation, gender identity, pregnancy, disability, or any other characteristic protected by law. We offer a welcoming and inclusive environment in service to one another, our products, the diverse consumers we represent, and the communities we call home. We do all of this with kindness, empathy and respect for each other. The above is intended to describe the general content of and requirements for the performance of this job. It should not be construed as an exhaustive statement of duties, responsibilities or physical requirements.