NeoSigma

Founding Business Generalist

The Role

We are looking for a Founding Business Generalist to help build NeoSigma alongside the founders. You will work across customers, product, GTM, strategy, and business operations, with a strong bias toward execution.

You will own ambiguous, business-critical problems, develop a point of view from first principles, and build the systems and processes that make what works repeatable.

What you'll do

  • Own high-priority work across sales, pricing, contracts, growth, and company operations.
  • Move customer opportunities from research and discovery through proposals, pilots, procurement, and close.
  • Turn customer conversations into sharper product, positioning, pricing, and company strategy.
  • Research new markets and business problems, form clear recommendations, and drive execution.
  • Run rapid experiments across outbound, content, partnerships, pricing, and new markets.
  • Build lightweight systems, automations, and processes that create leverage across the company.

What we look for

  • Extremely high agency. You create structure, move fast, and do not wait for instructions.
  • Strong technical fluency. You understand complex technology and are energized by operating at the interface of product, customers, and the market.
  • Sharp commercial and product instincts, with the ability to translate technical capabilities into clear customer value.
  • Exceptional research, writing, and communication skills, with the judgment to turn ambiguous information into action.
  • Comfort moving between strategy and hands-on execution, whether preparing a customer proposal, researching pricing, coordinating a contract, or shaping a product decision.
  • Experience as a founder, early-stage operator, or investor is a strong plus.

Our Core Values

  • Customer Obsession - We start with the customer and work backwards. We aim to earn trust through consistent delivery, thoughtful listening, and by obsessing over customers.
  • Intellectual Honesty - We operate with high trust and low ego. Ideas matter more than titles, and we communicate openly and directly while assuming good intent, even in strong disagreement.
  • Bias for Action - We set high standards and move quickly to meet them. We prefer building and learning with customers over debating in the abstract, and we iterate based on real feedback.
  • Extreme Ownership - We take responsibility for outcomes, not just tasks. Ownership means seeing problems through to completion and ensuring solutions truly work in practice.

Benefits and perks

  • Competitive salary plus meaningful equity package
  • Comprehensive medical benefits and generous PTO
  • Flexible work arrangements
  • Direct impact on company direction and technical decisions
  • High ownership and the opportunity to make a career-defining impact


As a founding member, you’ll help define the technical foundation of NeoSigma. Your scope will grow with the company, from owning core systems end-to-end to shaping architecture, hiring, and engineering culture. This role has a natural path toward technical leadership or engineering management as the team scales.


About Us

NeoSigma is a product-driven research lab building the intelligence layer that helps close the feedback loop between your customers, products, and AI systems.

We are a small, intensely technical team of researchers and engineers who have trained frontier-scale models and widely used AI products and agents at MIT, Parallel Web, Essential AI, Apple, and Amazon.

Product and Growth

Remote

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