At Pathos, we’re reimagining what’s possible in oncology drug development.

Founded by the team that built and scaled Tempus Labs, home to the world’s largest library of clinical and molecular data, Pathos is on a mission to revolutionize precision medicine in cancer. We’re using AI and machine learning not as buzzwords, but as fundamental tools to understand biology, identify precise disease drivers, and match patients to the therapies they truly need.

Our vision is bold: to create a new model for drug discovery and development, one rooted in deep data, integrated science, and rapid translation. We’re not building another pharma company, we’re building a platform to find better medicines, faster, and to get them to the right patients at the right time.

We’ve already begun assembling a portfolio of clinical-stage oncology assets, and we’re applying our technology to select the right indications, optimize clinical design, and increase the probability of success, from bench to bedside.

We believe that the current system moves too slowly, and too many patients are still waiting. That’s why we’re here. That’s why Pathos exists.

If you’re driven by purpose, excited by complexity, and eager to work alongside brilliant, kind, and mission-aligned teammates, we’d love to meet you.

We’re headquartered in New York City, with a distributed team across the U.S., and operate with the focus and agility of a startup while building with the scale and ambition of something much bigger.

Come help us build it.

The Role

As the founding IT team member, you will:

• Enable cross-functional teams to work effectively through secure and efficient IT infrastructure, while providing security consultation to help team members of varying technical expertise identify and mitigate their unique risk profiles
• Build security guardrails that protect our critical assets while enabling rapid innovation - finding the sweet spot between robust protection and operational efficiency
• Design and implement robust security systems protecting sensitive clinical and research data
• Scale cloud and on-premises systems, including network, compute, and storage infrastructure
• Lead security awareness initiatives and promote security-first practices
• Partner with development teams to ensure application security compliance
• Support laboratory systems and equipment maintenance
• Manage vendor relationships and third-party security assessments
• Have potential to grow into a leadership position as the team expands

This position is based in New York City and requires being on-site a minimum of 3 days per week, with the potential for additional days based on the onsite needs of the office. Hybrid work arrangements can be accommodated as appropriate. The role reports to the VP of Engineering.

Who you are

Required Qualifications:

• Extensive IT and information security experience
• Strong communication skills to engage team members of all technical backgrounds
• Proven track record building secure, scalable infrastructure
• Experience managing hybrid cloud/on-premises/colocation environments
• SSO and identity management system administration
• Experience managing workplace tools, including Google Workspace and Microsoft 365
• Experience administering both Mac and Windows systems

Preferred Qualifications:

• Healthcare or life sciences background
• HIPAA, GDPR, and healthcare security regulation knowledge
• Management experience
• Laboratory/scientific computing environment expertise
• Laboratory equipment support and security experience
• Familiarity with remote workstation administration, such as Active Directory