Research Associate I, Bioconjugation

Company Description
Zymeworks is a publicly listed (NASDAQ:ZYME) R&D and clinical-stage biopharmaceutical company dedicated to the discovery, development and commercialization of next-generation, bispecific and multifunctional biotherapeutics, initially focused on the treatment of cancer. Zymeworks' suite of complementary therapeutic platforms and its fully-integrated drug development engine provide the flexibility and compatibility to precisely engineer and develop highly-differentiated product candidates. We are  a global company headquartered in Vancouver, BC, with operations in Bellevue, WA, Dublin, Ireland, Singapore and Redwood City, CA. 

 

Why Work With Us

Nothing is more critical to our success than the quality of our team. The work we do is meaningful and impactful - we care about each other as well as the patients we serve. We offer challenging career opportunities, competitive benefits and an environment that recognizes and rewards performance.


This role will be located in Vancouver, BC and is full-time onsite.


What You'll Do

  • Performs multistep bioconjugation experiments to generate antibody and protein conjugates (milligram to gram scales) for in vitro and in vivo evaluation.
  • Applies modern analytical techniques to characterize the biophysical properties and stability of proteins and protein-conjugates.
  • Proposes and executes technology development efforts to advance techniques related to antibody drug conjugate (ADC) design, preparation and characterization.
  • Documents raw and analyzed data. Collaborates with colleagues to interpret results and design follow-up experiments.
  • Prepares written reports for internal and external use; makes presentations to team and department regularly.
  • Seeks to understand ongoing developments and innovations in ADCs through attention to scientific literature and internally generated data.
  • Adheres to Zymeworks standard procedures for generating, documenting, and archiving data, maintaining an accurate, up-to-date electronic laboratory notebook.
  • Maintains a safe, organized, and operational lab.
  • Conducts all activities in accordance with scientific standards, OS&H regulations and established Zymeworks’ policies and practices.
  • Actively works to foster an environment of effective and collaborative working relationships across the organization.

What You'll Bring

  • BSc in biochemistry, chemistry or a similar field required.
  • 8+ months working in a relevant laboratory as part of an internship, co-op job or summer placement.
  • Proven record of aseptic technique using a biosafety cabinet.
  • Experience with protein purification.
  • Experience with HPLC instrumentation and software.
  • Experience with automated liquid handling instrumentation and software.
  • Knowledge in protein biochemistry and methods for protein characterization.
  • General familiarity of antibody and ADC structure and function.

Total Rewards

We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth. We regularly benchmark our compensation against leading biotechnology companies in our geographies. 


The base salary range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position in the location for which the job is posted and does not include bonus, equity, or benefits. Within the range, individual pay is determined by a variety of factors and the salary offered may vary depending on the successful candidate’s location and qualifications (including, but not limited to, job-related knowledge, education, training, skills, and experience).


Our total rewards package that includes: 

  • Industry leading vacation and paid time off
  • Exceptional medical, dental and vision benefits by country
  • Zymelife health and wellness benefits
  • Matching RRSP / 401K / Pension program
  • Employee Share Purchase Program
  • Employee Equity Program
  • Paid time off to volunteer in your community


This role is not eligible for relocation or immigration support. 

 

All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin or disability.

 

NOTE TO AGENCIES:  Zymeworks values our relationships with our recruiting partners.  We only accept resumes from those partners who have been contracted with us. Zymeworks is not responsible for any fees related to resumes that are unsolicited or are received without contract.  

The pay range for this role is:

51,750 - 79,350 CAD per year (CA)

Research & Development

Vancouver, Canada

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